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Mudanpi ( Tree Peony Root)---牡丹皮(powder100g/bottle)

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Product Description

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Mudanpi is the dried root bark of Paeonia sufruitcosa Andr.,pertaining to Ranunculaceae. The root is collected in fall. After the minor root , earth and sands are removed, the bark is peeled from the root, and then sun dried The raw form is used or after stir-baked with wine.

[ Medicinal Properties ]: Bitter, pungent, and slightly cold; relate to heart, liver and kidney meridians.

[ Medicinal Efficacies ]: Clear heat, cool blood; activate blood and resolve stasis.

[ Usage and Dosage ]: 6-12g. To activate blood and resolve stasis, it is stir-baked with wine.

[ Precautions ]: Be cautious with blood deficiency with cold, excessive menstruation and for pregnant woman.
 
[ Clinical Applications ]: 1. Warm toxinosis, macula, blood heat, hematemesis and epistaxis    Mudanpi treats macula due to warm toxinosis with Zhizi, Dahuang and Huangqin. For heat entering nutrient-blood, manifesting as macula, hematemesis and epistaxis caused by accelerated blood circulation, usually it is combined with Shuijiujiao, Shengdihuang and Chishao. In case of hematemesis and epistaxis due to blood heat, it is in combination with Dahuang, Daji and Qiancaogen; for example in Shihui Powder.
 
2. Warm Disease, damage to yin, yin deficiency with fever, night fever relieved in the morning, anhidrosis and bone-steaming     It is good at latent heat in yin level, so is the essential medicinal to treat bone-steaming  without sweating, usually combineed with BieJia, Zhimu and Shengdihuang; for example in Qinghao Biejia Decoction.
 
3. Stasis, amenorrhea, dysmenorrheal, lump and tumor     Usually it is with Taoren, Chuanxiong and Guizhi, such as in Guizhi Fuling Pills.
 
4. Abscess, swelling, sores, toxin and intestinal abscess in early stage      For external abscess, usually it is combined with Jinyinhua, Lianqiao and Baizhi. Also it treats intestinal abscess in early stage due to accumulation of stasis and heat, combined with Dahuang and Taoren; for example in Dahuang Mudanpi Decoction.
 
牡丹皮为毛茛科植物牡丹Paeonia suffruticosa Andr.干燥根皮。产于安徽、山东等地。秋季采挖根部,除去细根,剥取根皮,晒干。生用或酒炙用。
      
【药性】苦、甘,微寒。归心、肝、肾经。       
 
【功效】清热凉血,活血祛瘀。       
 
【应用】        1.温毒发斑,血热吐衄。本品苦寒,入心肝血分。善能清营分、血分实热,功能清热凉血止血。治温病热入营血,迫血妄行所致发斑、吐血、衄血,可配水牛角、生地黄、赤芍等药用;治温毒发斑,可配栀子、大黄、黄芩等药用,如牡丹汤(《圣济总录》);若治血热吐衄,可配大黄、大蓟、茜草根等药用,如十灰散(《十药神书》);若治阴虚血热吐衄,可配生地黄、栀子等药用,如滋水清肝饮(《医宗己任篇》)。       
 
2.温病伤阴,阴虚发热,夜热早凉、无汗骨蒸。本品性味苦辛寒,入血分而善于清透阴分伏热,为治无汗骨蒸之要药,常配鳖甲、知母、生地黄等药用,如青蒿鳖甲汤(《温病条辨》)。       
 
3.血滞经闭、痛经、跌打伤痛。本品辛行苦泄,有活血祛瘀之功。治血滞经闭、痛经,可配桃仁、川芎、桂枝等药用,如桂枝茯苓丸(《金匮要略》);治跌打伤痛,可与红花、乳香、没药等配伍,如牡丹皮散(《证治准绳》)。        4.痈肿疮毒。本品苦寒,清热凉血之中,善于散瘀消痈。治火毒炽盛,痈肿疮毒,可配大黄、白芷、甘草等药用,如将军散(《本草汇言》);若配大黄、桃仁、芒硝等药用,可治瘀热互结之肠痈初起,如大黄牡丹皮汤(《金匮要略》)。       
 
【用法用量】煎服,6—12g。清热凉血宜生用,活血祛瘀宜酒炙用。       
 
【使用注意】血虚有寒、月经过多及孕妇不宜用。       
 
【古籍摘要】        1.《神农本草经》:“主寒热,中风瘈疭、痉、惊痫邪气,除坚癥瘀血留舍肠间,安五脏,疗痈疮。”        2.《名医别录》:“下水,止烦渴,散颈下核,痈肿。”        3.《本草纲目》:“滋阴降火,解斑毒,利咽喉,通小便血滞。”       
 
【现代研究】:        1.化学成份:本品含牡丹酚、牡丹酚苷、牡丹酚原苷、牡丹酚新苷,并含芍药苷、氧化芍药苷、苯甲酰芍药苷、没食子酸、挥发油、植物甾醇、苯甲酸、蔗糖、葡萄糖等。      
  2.药理作用:所含牡丹酚及其以外的糖苷类成分均有抗炎作用;牡丹皮的甲醇提取物有抑制血小板作用;牡丹酚有镇静、降温、解热、镇痛、解痉等中枢抑制作用及抗动脉粥样硬化、利尿、抗溃疡、促使动物子宫内膜充血等作用;牡丹皮能显著降低心输出量;其乙醇提取物、水煎液能增加冠脉血流量;牡丹皮水煎剂及牡丹酚和除去牡丹酚的水煎液均有降低血压的作用。所含牡丹酚及芍药苷、苯甲酰芍药苷、苯甲酰氧化芍药苷等,均有抗血小板凝聚作用;牡丹皮水煎剂对痢疾杆菌、伤寒杆菌等多种致病菌及致病性皮肤真菌均有抑制作用,       
 
3.临床研究:用重用牡丹皮组成的复方,治疗原发性血小板减少性紫癜32例,效果尚佳(中西医结合杂志,1985,4:245);单用牡丹皮水煎服,治疗高血压7例,近期疗效较好(辽宁医学杂志,1960,7:48);用牡丹皮清水浸泡后的蒸馏液滴鼻,治疗过敏性鼻炎,有效率为87.1%(湖南医药杂志,1983,4:24);用3.5%丹皮酚霜外涂皮损处,治疗急性湿疹27例,治愈8例,显效5例,好转6例(中医杂志,1983,10:19)。

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