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Tinglizi (Peperweed Seed or Tansymustard Seed)---葶苈子

Price:
$7.87
Weight:
1.00 LBS
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Calculated at checkout


Product Description

It is the dried ripe seed of Lepidium apetalum Willd. and Descurainia Sophia (L.) Webb ex Prantl, family Cruciferae. The former is habitually called "Beitinglizi", the latter "Nantinglizi". The plants are cut in summer when the fruits are ripe and dried in the sun. The seeds are rubbed out and the impurities are removed. The raw slices or stir-baked ones are used.

[ Medicinal Properties ]: Pungent, bitter and extremely cold; relate to lung and urinary bladder meridians.

[ Medicinal Efficacies ]: Purge lung to relieve dyspnea; induce diuresis to relieve edema.

[ Clinical Applications ]: 1. Phlegm-fluid accumulation     To treat phlegm-fluid accumulation resulting in cough and dyspnea, fullness in chest, being unable to lie and general edema, it is combined with Dazao in Tingli Dazao Xiefei Decoction.

2. Edema, ascites in chest and abdomen, difficult urination       For damp-heat accumulation with abdominal edema, it is used together with Fangji, Jiaomu and Dahuang in Jishu Lihuang Pills; for thoracic accumulation syndrome with ascites in chest and hypochondrium, with Xingren, Dahuang and Mangxiao in Daxianxiong Pills. In recent years, it is used to treat exudative pleurisy and pleural effusion.

In recent years, it is ground for oral administration or combined with Fuzi and Huangqi to treat pulmonary heart disease and heart failure with edema and dyspnea effectively.

[ Usage and Dosage ]:3-9G. Decoct wrapped.

[ Medicinal Comparison]: Similarities: Sangbaipi and Tinglizi can purge lung to relieve dyspnea and induce diuresis to relieve edema and so they are effective for cough and dyspnea due to lung heat, edema and difficult urination.

Differences: Sangbaipi is sweet and cold and rather effective for clearing lung heat with its mild action, so it usually treats cough and dyspnea due to lung heat and edema of mild type. Tinglizi is bitter and cold and mainly effective for purging phlegm-fluid retention in lung with violent purging powder, and so it usually treats phlegm-fluid accumulation in lung, cough and dyspnea with quick breathing, ascites in chest and abdomen, edema and distending fulleness of excess syndrome.

葶苈子为十字花科植物独行菜 Lepidium apetalum Willd.或播娘蒿 Descurinia sophia (L.) Webb ex Prantl的成熟种子。前者称“北葶苈”,主产于河北、辽宁、内蒙古、吉林等地;后者称“南葶苈”,主产于江苏、山东、安徽、浙江等地。夏季果实成熟时采割植株,晒干,搓出种子,除去杂质,生用或炒用。

       【药性】苦、辛,大寒。归肺、膀胱经。        【功效】泻肺平喘,利水消肿。       
 
【应用】        1.痰涎壅盛,喘息不得平卧。本品苦降辛散,性寒清热,专泻肺中水饮及痰火而平喘咳。常佐大枣以缓其性,如葶苈大枣泻肺汤(《金匮要略》)。还常配苏子、桑白皮、杏仁等共用。       
 2.水肿,悬饮,胸腹积水,小便不利。本品泄肺气之壅闭而通调水道,利水消肿。治腹水肿满属湿热蕴阻者,配防己、椒目、大黄,即已椒苈黄丸(《金匮要略》);治结胸、胸水,腹水肿满,配杏仁、大黄、芒硝,即大陷胸丸(《伤寒论》)。       
 
【用法用量】煎服,5~10g;研末服,3~6g。       
 
【鉴别用药】桑白皮与葶苈子均能泻肺平喘,利水消肿,治疗肺热及肺中水气,痰饮咳喘以及水肿,常相须为用。桑白皮甘寒,药性较缓,长于清肺热,降肺火,多用于肺热咳喘,痰黄及皮肤水肿;而葶苈子力峻,重在泻肺中水气、痰涎,对邪盛喘满不得卧者尤宜,其利水力量也强,可兼治臌胀、胸腹积水之证。       
 
【古籍摘要】        1.《神农本草经》:“主癥瘕积聚结气,饮食寒热,破坚逐邪,通利水道。”       
 
2.《名医别录》:“下膀胱水,伏留热气,皮间邪水上出,面目浮肿。身暴中风热痱痒,利小腹。”       
 
3.《开宝本草》:“疗肺痈上气咳嗽,定喘促,除胸中痰饮。”       
 
【现代研究】        1.化学成分:播娘蒿种子含有强心苷类:如毒毛旋花子苷配基,伊夫单苷,葶苈子苷,伊夫双苷、异硫氰酸类:有葡萄糖异硫氰酸盐的降解产物,异硫氰酸苄酯,异硫氰酸烯丙酯,异硫氰酸丁烯酯。脂肪油类:油中主要含亚麻酸、亚油酸、油酸、芥酸、棕榈酸、硬脂酸。        独行菜的种子含芥子苷,脂肪油,蛋白质,糖类。       
 
 2.药理作用:两种葶苈子提取物,均有强心作用,能使心肌收缩力增强,心率减慢,对衰弱的心脏可增加输出量,降低静脉压。尚有利尿作用。葶苈子的苄基芥子油具有广谱抗菌作用,对酵母菌等2O种真菌及数十种其它菌株均有抗菌作用。葶苈子在很低剂量,即可发挥显著的抗癌效果。       
 
 3.临床研究:葶苈子对心血管疾病的治疗有重要意义,现临床多用治心力衰竭。如用强心栓(葶苈子、生黄芪、赤芍等)治疗充血性心力衰竭,总有效率为91.1%。(中医药学报,1992,2:79);用葶苈子降血脂胶囊(葶苈子、山楂、茵陈蒿等)治疗高脂血症,疗效确切(医学研究通讯,1999,9:9);治结核性渗出性胸膜炎,总有效率为100%(湖南中医杂志,1993,4:46);通淋排石方剂中加用葶苈子15~20g,治多例尿路结石病人有更好疗效(中医杂志,2000,10:637);生葶苈子去壳内服,治疗急性咽炎患者240例,痊愈221例,好转15例、无效4例(四川中医,1993,6:50);应用刺蒺藜糊(葶苈子、刺蒺藜)治疗牙齿敏感症,总有效率95.4%(四川中医,1997,4:52);炒葶苈子外敷治疗II度 、深Ⅱ度烧伤、表皮擦伤患者多例、效果良好(基层中药杂志,1999,2:63)。       
 
 4.不良反应:有服道葶苈子发生过敏反应者,表现为全身皮肤丘疹伴搔痒,偶发生过敏性休克,初起可见胸闷憋气,恶心呕吐,心慌,继之皮肤瘙痒,烦燥不安,颈项胸腹满布皮疹,进而面色口唇苍白,冷汗出,呼吸困难,心音低,血压下降。救治方法,应给予抗过敏、抗休克治疗,必要时对症处理。程度轻者,停药后可自行缓解。       

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