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Tufuling ( Glabrous Greebrieer Rhizome)---土茯苓(powder100g/bottle)

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Tufuling is the diredrhizome of Smilax glabra Roxb., pertaining to Lilaceae. It is collected in summer and fall. After the fibrous root is removed, it is washed ad then sun dried. Also the fresh one can be cut into thin slices to dry. The raw form is used.

[ Medicinal Properties ]: Sweet, bland and neutral; relate to liver and stomach meridians.

[ Medicinal Efficacies ]: Relieve toxicity, dispel dampness; ease joint movement.

[ Usage and Dosage ]: 15- 60g. Also it is used externally.

[ Precautions ]: Be cautious with deficiency of liver-kidney yin. During administration, avoid drinkig tea.
 
[ Clinical Applications ]: 1. Syphilis and muscular constriction of four limbs     Tufuling is the most significant medicinal to treat syphilis. It is used by itself of large dosage or combined with Jinyinhua, Baixianpi and Gancao; for example in Fuling Tufuling Decoction. For muscular constriciton of four limbs due to toxication by using mercurial, usually it is combined with Yiyiren, Fangfeng and Mugua.
 
2. Abscess, swelling, sore, toxin, stranguria, leucorrhea, eczema and itching      It itreats flare and ulceration in abscess and sore, by itself after ground into powder and mixed with vinegar, to paste externally. For heat stranguria, it is combined with Pugongying and Cheqianzi. In case of pruritus vulvae and leucorrhea , it is in combination with Cangzhu, Huangbo and Kushen. Also it treats skin itching due to damp-heat, combined with Difuzi, Baixianpi and Yinchen.

土茯苓为百合科植物光叶菝葜Smilax glabra Roxb.的干燥块茎。长江流域及南部各省均有分布。夏、秋二季采收,除去残茎和须根,洗净,晒干;或趁鲜切成薄片,干燥,生用。
      
【药性】甘、淡,平。归肝、胃经。       
 
【功效】解毒,除湿,通利关节。       
 
【应用】        1.杨梅毒疮,肢体拘挛。本品甘淡,解毒利湿,通利关节,又兼解汞毒,故对梅毒或因梅毒服汞剂中毒而致肢体拘挛、筋骨疼痛者疗效尤佳,为治梅毒的要药。可单用本品水煎服,如土萆薢汤(《景岳全书》);也可与金银花、白鲜皮、威灵仙、甘草同用;若因服汞剂中毒而致肢体拘挛者,常与薏苡仁、防风、木瓜等配伍治之,如搜风解毒汤(《本草纲目》)。       
 
2.淋浊带下,湿疹瘙痒。本品甘淡渗利,解毒利湿,故可用于湿热引起的热淋、带下、湿疹湿疮等证。常与木通、萹蓄、蒲公英、车前子同用,治疗热淋;《滇南本草》单用本品水煎服,治疗阴痒带下;若与生地、赤芍、地肤子、白鲜皮、茵陈等配伍,又可用于湿热皮肤瘙痒。       
 
3.痈肿疮毒。本品清热解毒,兼可消肿散结,如《滇南本草》以本品研为细末,好醋调敷,治疗痈疮红肿溃烂;《积德堂经验方》将本品切片或为末,水煎服或入粥内食之,治疗瘰疬溃烂;亦常与苍术、黄柏、苦参等药配伍同用。       
 
【用法用量】煎服,15~60g。外用适量。        【使用注意】肝肾阴虚者慎服。服药时忌茶。       
 
【古籍摘要】        1.《本草纲目》:“健脾胃,强筋骨,去风湿,利关节,止泄泻。治拘挛骨痛,恶疮痈肿。解汞粉、银朱毒。”       
 2.《本草备要》:“治杨梅疮毒,瘰疬疮肿。”        3.《本草正义》:“土茯苓,利湿去热,能入络,搜剔湿热之蕴毒。其解水银、轻粉毒者,彼以升提收毒上行,而此以渗利下导为务,故专治杨梅毒疮,深入百络,关节疼痛,甚至腐烂,又毒火上行,咽喉痛溃,一切恶症。”       
 
【现代研究】        1.化学成分:本品含落新妇苷、异黄杞苷、胡萝卜苷、3,5,4’-三羟基芪、(-)表儿茶精L、琥珀酸、β-谷甾醇等皂苷、鞣质、黄酮、树脂类等,还含有挥发油、多糖、淀粉等。      
  2.药理作用:本品所含落新妇苷有明显的利尿、镇痛作用;对金黄色葡萄球菌、溶血性链球菌、大肠杆菌、绿脓杆菌、伤寒杆菌、福氏痢疾杆菌、白喉杆菌和炭疽杆菌均有抑制作用;对大鼠肝癌及移植性肿瘤有一定抑制作用;经动物试验推断:本品可通过影响T淋巴细胞释放淋巴因子的炎症过程而选择性地抑制细胞免疫反应;此外尚能缓解汞中毒;明显拮抗棉酚毒性。       
3.临床研究:土茯苓及其制剂,在临床上常用于梅毒和淋病,无论是改善临床症状或血清变化均取得了较好的疗效。近年土茯苓又用于治疗多种疾病,如:用土茯苓30g,配伍野菊花、忍冬藤、虎杖、透骨草,水煎浸泡熏洗患处,治疗类丹毒79例(从事鱼、肉类加工人员由于猪丹毒杆菌经皮损侵入所引起的如丹毒样皮肤急性感染性疾病),痊愈72例,好转6例(中医杂志2001,11:649);用土茯苓研末与仙人掌按2:1比例捣烂加少许鸡蛋清混匀为膏状敷患处,用于急性睾丸炎红、肿、热、痛而无脓液者,治疗26例,均获痊愈(中医杂志2001,11:64);用土茯苓合剂(土茯苓、薏苡仁、麦芽、谷芽、乌梅、瓜蒌等),治疗食道贲门癌28例,能改善症状延长存活期,疗效显著(基层中药杂志2000,1:57)。
此外,土茯苓尚可用于心律失常、痛风症、银屑病、扁平疣、滴虫性阴道炎、肾盂肾炎、乙型肝炎、急性扁桃体炎、钩端螺旋体病以及治疗慢性铅中毒,缓解激素撤减困难和鸦片依赖症状等。

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