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Lizhihe ( Litchi seed)---荔枝核

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Product Description

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It is the dried ripe fruit of Litchi chinensis Sonn, family Sapindaceae. The ripe fruits are collected in summer. With rind and pulp-like seed skin removed, they are dried in the sunshine. It is pounded or stir-baked with salty water for using.

[ Medicinal Properties ]: Sweet, slightly bitter and warm; relate to liver and kidney meridians.

[ Medicinal Efficacies ]: Soothe liver and dissipate stagnation; dispel cold and relieve pain.

[ Clinical Applications ]: 1. Cold type hernia with abdominal pain, swelling pain in testicle       It treats congealing cold and qi stagnation in liver meridian manifested as hernia pain and swelling pain in testicle, in combinatin with Wuzhuyu, Xiaohuixiang and Juhe, such as Shanqi Neixiao Pills. With Longdan, Zhizi and Chuanliannzi, it treats excess fire in liver meridian and down-pour of damp-heat manifested as reddish and swelling scrotum.

2. Epigastric pain     It is combined with Muxiang, in Lixiang Powder to treat stagnation of liver qi causing epigastric pain.

3. Dysmenorrhea or postpartum abdominal pain       It treats qi stagnation and blood stasis resulting in dysmenorrhea or postpartum abdominal pain, in combination with Xiangfu in Juantong Powder.

[ Usage and Dosage ]: 4.5-9g.

荔枝核为无患子科植物荔枝Litchi chinensis Sonn.的成熟种子。主产于福建、广东、广西等地。夏季采摘成熟果实,除去果皮及肉质假种皮,洗净,晒干。生用或盐水炙用。用时打碎。

【药性】辛、微苦,温。归肝、胃经。        【功效】行气散结,散寒止痛。       
 
【应用】        1.疝气痛,睾丸肿痛。本品主入肝经,味辛能行,味苦能泄,性温祛寒,有疏肝理气、行气散结、散寒止痛之功。治寒凝气滞之疝气痛、睾丸肿痛,可与小茴香、青皮等同用,如荔核散(《世医得效方》);或与小茴香、吴茱萸、橘核等同用,如疝气内消丸(《北京市中药成方选集》);若睾丸肿痛属湿热者,可配龙胆草、川楝子、大黄等同用。      
 
  2.胃脘久痛,痛经,产后腹痛。本品辛行苦泄温通,入肝胃经,有疏肝和胃、理气止痛作用。治肝气郁结、肝胃不和之胃脘久痛,可与木香研末服,如荔香散(《景岳全书》);若肝郁气滞血瘀之痛经及产后腹痛,可与香附研末服,如蠲痛散(《妇人大全良方》),或酌加川芎、当归、益母草等同用,疗效更好。       
 
【用法用量】煎服,4.5~9g。或入丸、散剂。       
 
【古籍摘要】        1.《本草衍义》:“治心痛及小肠气。”        2.《本草纲目》:“行散滞气,治颓疝气痛,妇人血气痛。”       
 
 3.《本草备要》:“入肝肾,散滞气,辟寒邪,治胃脘痛,妇人血气痛。”       
 
【现代研究】        1.化学成分:本品含挥发油,油中成分有3-羟基丁酮等,还有α-亚甲环丙基甘氨酸。       
 
2.药理作用:本品所含α-亚甲环丙基甘氨酸给小鼠皮下注射,有降血糖作用;荔枝核水或醇提取物、荔枝核油具有调血脂和抗氧化作用,能降低动物血清总胆固醇(TC)、及甘油三酯(TG);能对抗ALX所致的自由基损伤,提高抗氧化酶SOD活性;有对抗鼠伤寒沙门氏菌的诱变作用;荔枝核水提取物对乙型肝炎病毒表面抗原有抑制作用。       
 
 3.临床研究:以荔枝核烘干为末口服,治疗糖尿病,治愈7例40岁以上中老年非胰岛素依赖型无合并症的糖尿病患者(辽宁中医杂志,1986,8:31);另以荔枝核片(每片0.3g)口服,治疗30例轻型和中型糖尿病,经3~6个月治疗,总有效率83.33%(中成药,1991,11:24)。       

 


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